Perspective: stem cells react! Cell lineages as complex adaptive systems.
نویسنده
چکیده
It may be argued that adult stem cell processes or, more precisely, the cell lineages that arise from them, represent complex reactive or adaptive systems. Approaching hematopoietic and other stem cell lineages from this perspective has direct bearing on current debates regarding the plasticity of these lineage systems as well as on interpretation and modeling of clinical data regarding many diseases.
منابع مشابه
Understanding cell lineages as complex adaptive systems.
Stem cells may be considered complex reactive systems because of their vast number in a living system, their reactive nature, and the influence of local environmental factors (such as the state of neighboring cells, tissue matrix, stem cell physiological processes) on their behavior. In such systems, emergent global behavior arises through the multitude of local interactions among the cell agen...
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ورودعنوان ژورنال:
- Experimental hematology
دوره 32 1 شماره
صفحات -
تاریخ انتشار 2004